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FIGURE 2. Examples of ROIs defined by semiautomated method and simple threshold method with 30% threshold. Qualities of semiautomated (A) and threshold (B) ROIs in patient with CL of 17.5 mL/min/1.73 m2 were graded as fair and poor, respectively. Semiautomated (C) and threshold (D) methods provided good and poor results, respectively, in patient with CL of 79.9 mL/min/1.73 m2 and relative hypofunction of left kidney. Use of simple threshold overestimates renal area, especially for left side.