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FIGURE 1. Effects of anatomic standardization. Top row represents stereotactic reference MR image set (REF) averaged across 6 monkeys. Second through bottom rows represent SD maps created from MR images (scalp and skull removed) across 6 monkeys with stereotactic realignment alone and no linear scaling (NS), with linear scaling (LS), and with linear scaling and nonlinear warping (LS+NW), respectively. Millimetric scales represent slice levels from anteroposterior commissures (ACPC) in stereotactic space. Areas of higher SDs indicate greater anatomic mismatches. Dramatic reduction of mismatches is seen from NS to LS, and further improvement is seen from LS to LS+NW.
