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FIGURE 5. Example of linear graphic analysis using Logan-Patlak fits. Slopes of fits represent the distribution volumes. ROI(T) refers to radioactivity in region of interest at time t. CER = cerebellum; Cp(t) = plasma radioactivity corrected for metabolites (23);
0T Cp(t)dt = integral of plasma radioactivity over time from time zero to time t; LTC = lateral temporal cortex;
0T ROI(t)dt = integral of radioactivity in region of interest over time from time zero to time t.