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FIGURE 4. Reverse-phase HPLC analysis of FOP standard (A) and ¹⁸F radioactivity in representative samples of serum taken from control or etomoxir-treated rats 15 min after injection of FOP (B and C). Small levels of unidentified polar metabolites of FOP were observed in serum samples. Intact FOP composed 85.4% ± 1.4% and 96.7% ± 0.8% (P < 0.0001) of total radioactivity in serum 15 min after injection for control and etomoxir-treated rats, respectively.

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