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FIGURE 2. Effect of eniluracil (EU) on tumor visualization. Images are thin anteroposterior coronal and transaxial slices through tumors 110–120 min after intravenous injection of [18F]FU (FU). Spatial resolution of reconstructed images is 6–7 mm FWHM in the transaxial plane and 6 mm in the axial dimension. Tumor locations were verified by 18F marker images. Tumor weights and standardized uptake values (SUVs) were determined by direct measurements on excised tissues. (A) Tumors in legs (left [upper]: 1.3 g, SUV 1.05; right: 0.32 g, SUV 1.57) are clearly visualized relative to adjacent normal tissues. (B) Tumors (left: 0.22 g, SUV 0.61; right: 0.43 g, SUV 0.67) are less distinguishable, attributed in part to elevated bone uptake of 18F.
