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First published online April 20, 2009, 10.2967/jnumed.108.057232
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18F-FDG PET and 18F-FDG PET/CT for Assessing Response to Therapy in Esophageal Cancer

Bernd J. Krause1, Ken Herrmann1, Hinrich Wieder2 and Christian Meyer zum Büschenfelde3

1 Department of Nuclear Medicine, Technische Universität München, Munich, Germany; 2 Department of Radiology, Technische Universität München, Munich, Germany; and 3 Department of Internal Medicine, Technische Universität München, Munich, Germany


Figure 1
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FIGURE 1.  Coronal PET/CT (I), axial PET (II), CT (III), and PET/CT (IV) images of a patient with locally advanced adenocarcinoma of the esophagogastric junction (arrow) before (A) and 14 d after beginning (B) neoadjuvant chemotherapy. Fourteen days after initiation of neoadjuvant chemotherapy, tumor metabolic activity is marginally decreased (<35%). After completion of chemotherapy, more than 50% tumor cells were found in resected specimen.

 

Figure 2
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FIGURE 2.  Coronal PET/CT (I), axial PET (II), CT (III), and PET/CT (IV) images of a patient with locally advanced adenocarcinoma of the esophagogastric junction (arrow) before (A) and 14 d after beginning (B) neoadjuvant chemotherapy. Already 14 d after initiation of neoadjuvant chemotherapy, tumor metabolic activity is markedly decreased (>35%). After completion of chemotherapy, no viable tumor cells were found in resected specimen.

 





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