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First published online April 15, 2008, 10.2967/jnumed.107.049072
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Recombinant Human TSH–Assisted Radioactive Iodine Remnant Ablation Achieves Short-Term Clinical Recurrence Rates Similar to Those of Traditional Thyroid Hormone Withdrawal

R. Michael Tuttle1, Matvey Brokhin2, Gal Omry1, Andrew J. Martorella1, Steven M. Larson3, Ravinder K. Grewal3, Martin Fleisher4 and Richard J. Robbins5

1 Division of Endocrinology, Memorial Sloan-Kettering Cancer Center, New York, New York; 2 Division of Endocrinology, Geisinger Medical Center, Danville, Pennsylvania; 3 Division of Nuclear Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York; 4 Clinical Chemistry, Memorial Sloan-Kettering Cancer Center, New York, New York; and 5 Department of Medicine, Methodist Hospital, Houston, Texas


Figure 1
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FIGURE 1.  Study time line.

 

Figure 2
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FIGURE 2.  Kaplan–Meier curve showing time to recurrence in both rhTSH cohort and THW cohort. Longer time of follow-up for THW did not result in higher recurrence rates, because most recurrences in both groups were detected in first 24–36 mo after ablation.

 





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