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Adjuvant Intraarterial Injection of ¹³¹I-Labeled Lipiodol After Resection of Hepatocellular Carcinoma: Progress Report of a Case-Control Study with a 5-Year Minimal Follow-up

¹ Département d'Oncologie Médicale, Centre Eugène Marquis, Rennes, France; ² Département d'Imagerie Médicale, Centre Eugène Marquis, Rennes, France; ³ Service Des Maladies du Foie, CHRU Pontchaillou, Rennes, France; and ⁴ Département de Chirurgie Viscérale et de Transplantation Hépatique, CHRU Pontchaillou, Rennes, France

View larger version (9K): [in this window] [in a new window]   FIGURE 1.  Frequency and date of onset (years) of recurrences in control group (n = 28 [white bars]) and in 131I-lipiodol group (n = 28 [black bars]).

View larger version (8K): [in this window] [in a new window]   FIGURE 2.  Disease-free survival by postoperative adjuvant treatment (P < 0.03). Lip = lipiodol.

View larger version (7K): [in this window] [in a new window]   FIGURE 3.  Overall survival of patients receiving a single 131I-lipiodol postoperative injection or surgery alone (not statistically significant). Lip = lipiodol.

View larger version (41K): [in this window] [in a new window]   FIGURE 4.  CT scans of 2 patients showing slight 131I-lipiodol retention 7 d after 131I-lipiodol injection.