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First published online November 7, 2008, 10.2967/jnumed.108.052688
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Analysis of the Effects of Injecting Drug Use and HIV-1 Infection on 18F-FDG PET Brain Metabolism

Michalis F. Georgiou1, Ati Gonenc1, Drenna Waldrop-Valverde2, Russ A. Kuker1, Shabbir H. Ezuddin1, George N. Sfakianakis1 and Mahendra Kumar2

1 Department of Radiology, University of Miami School of Medicine, Miami, Florida; and 2 Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Miami, Florida


Figure 1
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FIGURE 1.  Two-dimensional MIP glass-brain representation showing areas of relative hypometabolism (A) and relative hypermetabolism (B) in HIV+/IDU+ group, compared with HIV–/IDU– controls. (C) Three-dimensional rendering of both hypermetabolism (red) and hypometabolism (green).

 

Figure 2
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FIGURE 2.  Two-dimensional MIP glass-brain representation showing areas of relative hypometabolism (A) and relative hypermetabolism (B) in HIV–/IDU+, compared with HIV–/IDU– controls. (C) Three-dimensional rendering of both hypermetabolism (red) and hypometabolism (green).

 

Figure 3
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FIGURE 3.  Two-dimensional MIP glass-brain representation showing areas of relative hypometabolism (A) and relative hypermetabolism (B) in HIV+/IDU+, compared with HIV–/IDU+. (C) Three-dimensional rendering of both hypermetabolism (red) and hypometabolism (green).

 





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