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First published online August 17, 2007, 10.2967/jnumed.107.040824
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Role of 99mTc-Octreotide Acetate Scintigraphy in Suspected Lung Cancer Compared with 18F-FDG Dual-Head Coincidence Imaging

Feng Wang1, Zizheng Wang1, Weixuan Yao1, Hong Xie2, Jie Xu1 and Li Tian3

1 Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; 2 Respiratory Department, Nanjing First Hospital, Nanjing Medical University, Nanjing, China; and 3 Respiratory Department, Nanjing Chest Hospital, Nanjing, China


Figure 1
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  		FIGURE 1.  A 46-y-old male patient with benign clear cell tumor. (A) CT scans showed abnormality in right upper lobe. (B) 18F-FDG coincidence images had intense uptake in lesion. (C) 99mTc-Octreotide images were negative in lesion.

 

Figure 2
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  		FIGURE 2.  A 75-y-old male patient with adenosquamous lung cancer in left upper lobe. (A) CT scans showed abnormality in left upper lobe. (B) 18F-FDG coincidence images had intense uptake in lesion (arrows). (C) 99mTc-Octreotide images showed intense uptake in primary tumor and pleura (arrows). (D) Adenosquamous lung cancer and pleural invasion were verified on histology.

 

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  		FIGURE 3.  A 57-y-old male patient with squamous lung cancer. (A) CT scans showed neoplasm high in upper lobe of right lung. (B) 18F-FDG coincidence images had focal uptake in lesion. (C) 99mTc-Octreotide images had focal high uptake in lesion. (D) Squamous lung cancer and pleura and rib invasion were verified on histology.

 

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  		FIGURE 4.  A 65-y-old woman with lung adenocarcinoma. (A) CT scans revealed brain metastasis and peripheral edema in left temporal lobe. (B) 18F-FDG images showed low uptake in brain lesion. (C) 99mTc-Octreotide images showed focal uptake in brain lesion.

 




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