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First published online August 17, 2007, 10.2967/jnumed.106.037705
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Application of 99mTc-Pertechnetate Scintigraphy to Microvascular Autologous Transplantation of the Submandibular Gland in Patients with Severe Keratoconjunctivitis Sicca

Lei Zhang1, Zheng-Hong Zhu2, Hao-Jie Dai3, Zhi-Gang Cai1, Chi Mao1, Xin Peng1 and Guang-Yan Yu1

1 Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China; 2 Department of Stomatology, Tong Ren Hospital, Beijing, China; and 3 Department of Nuclear Medicine, Tong Ren Hospital, Beijing, China


Figure 1
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  		FIGURE 1.  Scintigram showing normally functioning parotid and submandibular glands.

 

Figure 2
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  		FIGURE 2.  Scintigram showing seriously damaged functioning of all parotid and submandibular glands, indicating that they are not suitable for transplantation.

 

Figure 3
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  		FIGURE 3.  Scintigraphy series showing 99mTc-pertechnetate uptake by normal and transplanted (arrowheads) submandibular glands. About 0.5 mL of citric acid was applied at 20 min to stimulate salivary secretion.

 

Figure 4
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  		FIGURE 4.  Anterior (A) and lateral (B) scintigrams showing significant 99mTc-pertechnetate uptake in temporal region, indicating that transplanted gland (arrow) is revascularized and viable.

 

Figure 5
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  		FIGURE 5.  Anterior (A) and lateral (B) scintigrams showing no uptake of 99mTc-pertechnetate in temporal region, suggesting that transplanted gland (arrowhead) is not revascularized.

 

Figure 6
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  		FIGURE 6.  Anterior (A) and lateral (B) 180-min delayed scintigrams showing drainage of 99mTc-pertechnetate into orbit through Wharton's duct (arrowhead) of transplanted gland (arrow).

 

Figure 7
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  		FIGURE 7.  Anterior (A) and lateral (B) 120-min delayed scintigrams showing no secretion in orbit, indicating obstruction of Wharton's duct of transplanted gland (arrow) (more than 3 mo after operation).

 




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