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First published online July 13, 2007, 10.2967/jnumed.107.040253
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Prosthetic Vascular Graft Infection: The Role of 18F-FDG PET/CT

Zohar Keidar1,2, Ahuva Engel2,3, Aaron Hoffman2,4, Ora Israel1,2 and Samy Nitecki2,4

1 Department of Nuclear Medicine, Rambam Health Care Campus, Haifa, Israel; 2 B. Rappaport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel; 3 Department of Radiology, Rambam Health Care Campus, Haifa, Israel; and 4 Department of Vascular Surgery, Rambam Health Care Campus, Haifa, Israel


Figure 1
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  		FIGURE 1.  A 54-y-old man who had received right femoropopliteal bypass graft 3 mo previously. Infection was clinically suspected because of fever and local pain in right groin. 18F-FDG PET (center) demonstrates focus of increased tracer uptake in right groin (arrow), localized by PET/CT (right) to right femoropopliteal vascular graft as seen on CT (left, arrow). Graft was considered to be involved by infectious process. Diagnosis was confirmed at surgery, and infected graft was removed.

 

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  		FIGURE 2.  A 68-y-old man who had received left femoropopliteal bypass graft 18 mo previously. Infection was clinically suspected because of fever and infected surgical wound in medial aspect of left distal thigh. Coronal (top left) and transaxial (top right) 18F-FDG PET images show area of increased uptake in medial aspect of left thigh (arrows), localized by PET/CT image (bottom right) to soft-tissue swelling (arrow) adjacent to left femoropopliteal graft as seen on CT (bottom left). Patient responded rapidly to antibiotic therapy, and no vascular graft infection was evident on long-term follow-up of 14 mo.

 




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