JNM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

First published online June 15, 2007, 10.2967/jnumed.107.040535
This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in JNM
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Goetze, S.
Right arrow Articles by Bengel, F. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Goetze, S.
Right arrow Articles by Bengel, F. M.

Attenuation Correction in Myocardial Perfusion SPECT/CT: Effects of Misregistration and Value of Reregistration

Sibyll Goetze1,2, Tracy L. Brown1, William C. Lavely1, Zhe Zhang3 and Frank M. Bengel1

1 Division of Nuclear Medicine, Johns Hopkins University, Baltimore, Maryland; 2 Division of Nuclear Medicine, University of Alabama at Birmingham, Birmingham, Alabama; and 3 Division of Biostatistics, Johns Hopkins University, Baltimore, Maryland


Figure 1
View larger version (116K):
[in this window]
[in a new window]

  		FIGURE 1.  Software tool for realignment of misregistered CT and SPECT data. Using arrows of toolbar (left), CT can be moved in x-, y-, and z-axes relative to SPECT in order to match borders of left ventricle. In fusion images on right, dark lines depict myocardial borders of SPECT scan. In present case, CT was moved left and cranially to obtain alignment as illustrated by fused images in coronal, sagittal, and transaxial planes before and after realignment. Shifts are displayed in millimeters on toolbar and recorded for further analysis.

 

Figure 2
View larger version (92K):
[in this window]
[in a new window]

  		FIGURE 2.  Representative case of SPECT/CT misalignment before (A) and after (B) reregistration. Stress and rest short-axis slices and polar maps are displayed on left. (A) Noncorrected images (NC) show decreased radiotracer uptake in inferior wall, compared with attenuation-corrected images (AC). Inferior wall uptake is improved, suggesting attenuation artifact on noncorrected images. Anterior wall, however, shows reduced uptake on attenuation-corrected vs. noncorrected images. Significant misalignment of SPECT and CT is shown in fusion images on right. (B) After best possible realignment (right), tracer distribution in attenuation-corrected images at stress and rest is homogeneous (left). AC-R = attenuation-corrected images after reregistration.

 




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY THE JOURNAL OF NUCLEAR MEDICINE
Copyright © 2007 by the Society of Nuclear Medicine.