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Brown Fat Imaging with ¹⁸F-6-Fluorodopamine PET/CT, ¹⁸F-FDG PET/CT, and ¹²³I-MIBG SPECT: A Study of Patients Being Evaluated for Pheochromocytoma

¹ Department of Nuclear Medicine, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland; and ² Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland

View larger version (53K): [in this window] [in a new window]   FIGURE 1.  Patient 10 with pheochromocytoma showing 18F-F-DA uptake in supraclavicular BAT (black arrows) that corresponded to fat on coregistered CT (white arrows). At far right is maximum-intensity-projection image showing some uptake typical of 18F-F-DA (salivary gland, thyroid, vein in left upper extremity) and uptake in supraclavicular areas corresponding to BAT.

View larger version (54K): [in this window] [in a new window]   FIGURE 2.  Maximum-intensity-projection images of patient 18 with pheochromocytoma. 18F-FDG PET (A) shows typical BAT uptake in supraclavicular region extending into axilla and paravertebral regions. 18F-F-DA PET (B) and 123I-MIBG SPECT (C) show BAT uptake in supraclavicular regions. Uptake in paraspinal regions is best seen on 18F-FDG images.