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Use of ¹⁸F-FDG PET for Primary Treatment Strategy in Patients with Squamous Cell Carcinoma of the Oropharynx

¹ Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; ² Department of Otolaryngology, Bundang Jaesaeng General Hospital, Sungnam, South Korea; ³ Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; ⁴ Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; and ⁵ Department of Internal Medicine (Medical Oncology), Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

View larger version (8K): [in this window] [in a new window]   FIGURE 1.  Actuarial DFS in patients treated with surgery (n = 31) or RT (n = 21) as primary treatment modality (P = 0.036).

View larger version (8K): [in this window] [in a new window]   FIGURE 2.  Actuarial DFS using cutoff of 6.0 for SUV of 18F-FDG (low vs. high SUV, n = 27 vs. 25) (P = 0.036).

View larger version (8K): [in this window] [in a new window]   FIGURE 3.  Actuarial DFS in patients treated with surgery or RT as primary treatment modality in patients with tumor SUV 6.0 and SUV > 6.0. In 25 patients with SUV > 6.0, primary surgery followed by RT (n = 15) resulted in a statistically better survival than did RT with chemotherapy (n = 10) followed by surgical salvage (A; P = 0.043). In 27 patients with SUV 6.0, there was no significant difference between surgery plus RT (n = 16) and RT plus chemotherapy (n = 11) (B; P = 0.329).