JNM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in JNM
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Dinant, S.
Right arrow Articles by van Gulik, T. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Dinant, S.
Right arrow Articles by van Gulik, T. M.

Risk Assessment of Posthepatectomy Liver Failure Using Hepatobiliary Scintigraphy and CT Volumetry

Sander Dinant1, Wilmar de Graaf1, Bart J. Verwer1, Roelof J. Bennink2, Krijn P. van Lienden3, Dirk J. Gouma1, Arlène K. van Vliet1 and Thomas M. van Gulik1

1 Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands; 2 Department of Nuclear Medicine, Academic Medical Center, Amsterdam, The Netherlands; and 3 Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands


Figure 1
View larger version (51K):
[in this window]
[in a new window]

  		FIGURE 1.  Example of summed hepatobiliary scintigraphy image of frames between 150 and 350 s after intravenous injection of 85 MBq of 99mTc-mebrofenin. Regions of interest are drawn around total liver (gray) and future remnant liver (black). Future-remnant-liver region of interest is drawn around left liver as if in the case of a right hemihepatectomy.

 

Figure 2
View larger version (9K):
[in this window]
[in a new window]

  		FIGURE 2.  Bland–Altman plot showing mean uptake of 99mTc-mebrofenin in future remnant liver (FRL), as calculated in 46 hepatobiliary scintigraphy studies, versus differences in repeated calculations. Horizontal solid line indicates mean difference between the 2 calculations. Horizontal dashed lines indicate 95% limits of agreement (mean ± 1.96 SDs). No bias between the 2 observers was evident (P = 0.21 with paired t test). Ninety-three percent of values were within limits of agreement.

 

Figure 3
View larger version (12K):
[in this window]
[in a new window]

  		FIGURE 3.  ROC curves for liver failure (A) and liver failure–related mortality (B). Test results were considered positive when below cutoff value. Continuous staircase line represents uptake in future remnant liver (FRL), dotted staircase line represents FRL volume, and straight diagonal line is reference line (y = x). Area-under-curve (AUC) percentages are given beneath each graph, with 95% confidence interval between brackets. Cutoff values are encircled and noted.

 




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY THE JOURNAL OF NUCLEAR MEDICINE
Copyright © 2007 by the Society of Nuclear Medicine.