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Long-Term Nicorandil Therapy Improves Cardiac Sympathetic Nerve Activity After Reperfusion Therapy in Patients with First Acute Myocardial Infarction

¹ Department of Cardiovascular Medicine, Gunma University School of Medicine, Maebashi, Japan; and ² Cardiovascular Hospital of Central Japan, Gunma, Japan

View larger version (34K): [in this window] [in a new window]   FIGURE 1.  Comparison of cardiac 123I-MIBG scintigraphic findings for TDS (A), H/M ratio (B), and WR (C) in 2 groups. 3W = after 3 wk of therapy; 6 M = after 6 mo of therapy.

View larger version (9K): [in this window] [in a new window]   FIGURE 2.  Correlation between percent change in plasma PIIINP concentrations and that of TDS evaluated by 123I-MIBG scintigraphy from baseline to 6 mo after long-term nicorandil therapy.

View larger version (9K): [in this window] [in a new window]   FIGURE 3.  Correlation between percent change in contrast left ventriculographic LVEF and that of TDS evaluated by 123I-MIBG scintigraphy from baseline to 6 mo after long-term nicorandil therapy.