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Prediction of Absorbed Dose to Normal Organs in Thyroid Cancer Patients Treated with ¹³¹I by Use of ¹²⁴I PET and 3-Dimensional Internal Dosimetry Software

¹ Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York; and ² Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York

View larger version (20K): [in this window] [in a new window]   FIGURE 1.  Mean ± SD dose for each organ and for each subject. Right and left organ pairs and heart chamber and wall are graphed together. Maximum value on y-axis for salivary glands is 1.6 Gy/GBq; maximum value on y-axis for all other organs is 0.5 Gy/GBq.

View larger version (40K): [in this window] [in a new window]   FIGURE 2.  Integral DVHs by organ for each subject. y-Axis shows volume of organ (%) receiving at least the dose in Gy/GBq on x-axis. To show full range of doses and to demonstrate heterogeneity of distribution, range on x-axis varied from one organ group to the next. Arrows indicate DVHs for subject with high lesion load.