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SPECT-Guided CT for Evaluating Foci of Increased Bone Metabolism Classified as Indeterminate on SPECT in Cancer Patients

Wolfgang Römer1, Anton Nömayr1, Michael Uder2, Werner Bautz2 and Torsten Kuwert1

1 Clinic of Nuclear Medicine, University of Erlangen-Nuremberg, Erlangen, Germany; and 2 Institute of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany


Figure 1
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  		FIGURE 1.  99mTc-Dicarboxypropane diphosphonate SPECT/CT was performed with CT field of view from C4 to T4 in 74-y-old woman with breast cancer. SPECT images (left) show focally increased bone metabolism localized in vertebral body of C6. CT (right) discloses osteochondrosis in C6–C7, with vacuum phenomenon clearly matched to area of increased bone metabolism seen on fused images (middle). No osteolysis is detectable on CT. Top row is axial slices; bottom row, sagittal slices.

 

Figure 2
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  		FIGURE 2.  99mTc-Dicarboxypropane diphosphonate SPECT/CT was performed with CT field of view from C3 to T3 in 44-y-old woman with breast cancer. SPECT images (left) show focally increased bone metabolism localized in vertebral body of C5. CT (right) discloses clear-cut osteolysis in vertebral body of C5, with destruction of posterior corticalis clearly matched to area of increased bone metabolism seen on fused images (middle). No degenerative lesion is detectable on CT. Top row is axial slices; bottom row, sagittal slices.

 




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