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Regional Cerebral Glucose Metabolic Abnormality in Prader–Willi Syndrome: A ¹⁸F-FDG PET Study Under Sedation

¹ Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea; ² Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; ³ Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; and ⁴ Clinical Research Center, Samsung Medical Center and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea

View larger version (68K): [in a new window]   FIGURE 1.  Hypo- and hypermetabolic regions in PWS patients vs. healthy control subjects. These regions are displayed on surface rendered and transaxial images. Brain regions of abnormal glucose metabolism are displayed using height threshold of uncorrected P = 0.001 and extent threshold of 70 voxels, after removing age as a covariate of no interest. Numbers in each transaxial brain image indicate distance (mm) from the anterior commissure–posterior commissure plane.