JNM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in JNM
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Choi, J. Y.
Right arrow Articles by Kim, B.-T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Choi, J. Y.
Right arrow Articles by Kim, B.-T.

Focal Thyroid Lesions Incidentally Identified by Integrated 18F-FDG PET/CT: Clinical Significance and Improved Characterization

Joon Young Choi, MD1, Kyung Soo Lee, MD2, Hyung-Jin Kim, MD2, Young Mog Shim, MD3, O. Jung Kwon, MD4, Keunchil Park, MD4, Chung-Hwan Baek, MD5, Jae Hoon Chung, MD4, Kyung-Han Lee, MD1 and Byung-Tae Kim, MD1

1 Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 2 Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 3 Department of Thoracic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 4 Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; and 5 Department of Otorhinolaryngology–Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea


Figure 1
View larger version (10K):

[in a new window]
  		FIGURE 1.  Maximum SUV of benign and malignant focal thyroid lesions incidentally found on 18F-FDG PET/CT and undergoing further diagnostic confirmation. F/U = clinical follow-up.

 

Figure 2
View larger version (63K):

[in a new window]
  		FIGURE 2.  CT (left) and fused PET/CT (right) images of 65-y-old male patient with esophageal cancer showed abnormally high focal 18F-FDG uptake in left thyroid gland (maximum SUV = 33.1). CT attenuation of that lesion was very low (3.6 Hounsfield units), and surrounding thyroid gland had diffusely increased 18F-FDG uptake. Follicular adenoma with lymphocytic thyroiditis was confirmed after thyroidectomy.

 

Figure 3
View larger version (33K):

[in a new window]
  		FIGURE 3.  CT (left) and fused PET/CT (right) images of 56-y-old female patient with non–small cell lung cancer showed abnormal focal 18F-FDG uptake in right thyroid gland (maximum SUV = 5.3). That lesion had low CT attenuation (76 Hounsfield units) without calcification, and 18F-FDG uptake of surrounding thyroid gland was not increased. Papillary carcinoma was confirmed histopathologically.

 

Figure 4
View larger version (16K):

[in a new window]
  		FIGURE 4.  ROC curves of PET/CT when maximum SUV or maximum SUV with CT attenuation and 18F-FDG uptake pattern was applied for differentiation between benign and malignant focal thyroid lesions. The AUC of PET/CT was significantly increased when analysis of CT attenuation and 18F-FDG uptake pattern was added to maximum SUV (0.701 ± 0.079 vs. 0.878 ± 0.049; P < 0.01).

 




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY THE JOURNAL OF NUCLEAR MEDICINE
Copyright © 2006 by the Society of Nuclear Medicine.