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Low Efficacy of 18F-FDG PET for Detection of Uveal Malignant Melanoma Compared with 123I-IMP SPECT

Katsuhiko Kato, MD, PhD1, Toshinobu Kubota, MD2, Mitsuru Ikeda, MD, PhD3, Masanori Tadokoro, MD, PhD4, Shinji Abe, BSc, RT5, Satoshi Nakano, MSc, RT5, Masanari Nishino, BSc, RT5, Hidetoshi Kobayashi, MD, PhD6 and Takeo Ishigaki, MD, PhD1

1 Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan; 2 Department of Ophthalmology, National Hospital Organization, Nagoya Medical Center, Nagoya, Japan; 3 Department of Radiological Technology, Nagoya University School of Health Sciences, Nagoya, Japan; 4 Department of Radiology, Toyota Memorial Hospital, Toyota, Japan; 5 Department of Radiology, Nagoya University Hospital, Nagoya, Japan; and 6 Department of Radiology, Fujita Health University School of Health Science, Toyoake, Japan


Figure 1
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  		FIGURE 1.  Images of uveal malignant melanoma in patient 1 (60-y-old woman). Three-hour images by 123I-IMP SPECT (axial images (A), coronal images (B)) show no positive area. 123I-IMP SPECT images (axial images (C), coronal images (D)) obtained 24 h after injection show positive area in site corresponding to left ocular tumor. (E) MR images show high-intensity area on T1-weighted images (left) and low-intensity area on T2-weighted images (right) in left eye. Arrows indicate uveal malignant melanoma.

 

Figure 2
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  		FIGURE 2.  Images of uveal malignant melanoma in patient 13 (62-y-old woman). Three-hour images by 123I-IMP SPECT (axial images (A), coronal images (B)) show positive area in site corresponding to left eye tumor. 123I-IMP SPECT images (axial images (C), coronal images (D)) obtained 24 h after injection show positive area in site corresponding to left eye tumor. Arrows indicate uveal malignant melanoma. (E) 18F-FDG PET images show no positive area (images obtained by scan started 40 min after injection of 18F-FDG). (F) 18F-FDG PET images show no positive area (images obtained by scan started 3 h after injection of 18F-FDG).

 




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