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Linear Regression Model for Predicting Patient-Specific Total Skeletal Spongiosa Volume for Use in Molecular Radiotherapy Dosimetry

James M. Brindle1, A. Alexandre Trindade2, Amish P. Shah3, Derek W. Jokisch4, Phillip W. Patton5, J. Carlos Pichardo1 and Wesley E. Bolch1,6

1 Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida; 2 Department of Statistics, University of Florida, Gainesville, Florida; 3 M.D. Anderson Cancer Center Orlando, Orlando, Florida; 4 Department of Physics and Astronomy, Francis Marion University, Florence, South Carolina; 5 Department of Health Physics, University of Nevada–Las Vegas, Las Vegas, Nevada; and 6 Department of Biomedical Engineering, University of Florida, Gainesville, Florida


Figure 1
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FIGURE 1.  Comparison of original CT images and corresponding segmented images of skeletal spongiosa within 5 transverse views through 1 study cadaver. (A and B) Superior region of skull (pink: cranium). (C and D) Inferior regions of skull (pink: cranium; blue: mandible). (E and F) Upper torso region (orange: humeral heads; navy blue: clavicles; cyan: scapulae; teal: cervical vertebrae; magenta: ribs). (G and H) Midtorso region (green: sternum; yellow: thoracic vertebrae; cyan: scapulae; magenta: ribs). (I and J) Pelvic region (red: ossa coxae; light blue: sacrum).

 





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