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18F-FDG PET for Staging Breast Cancer in Patients with Inner-Quadrant Versus Outer-Quadrant Tumors: Comparison with Long-Term Clinical Outcome

Amy Tran, BS, Betty S. Pio, MS, Bahareh Khatibi, BS, Johannes Czernin, MD, Michael E. Phelps, PhD and Daniel H.S. Silverman, MD, PhD

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California



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FIGURE 1. (A) Distribution of PET findings of hypermetabolic foci for 99 OQ patients. (B) Distribution of PET findings of hypermetabolic foci for 42 IQ patients. EAx = extraaxillary; Ax = axillary; both = axillary and extraaxillary; none = no metastases.

 


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FIGURE 2. Whole-body coronal 18F-FDG PET scans of breast cancer patients, with arrows indicating extraaxillary metastases in chest and supraclavicular regions (A), metastasis in right axilla (B), and axillary and extraaxillary metastases in chest, lumbar, and iliac regions (C).

 


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FIGURE 3. Breakdown of clinical outcomes and PET findings for different primary-tumor locations.

 


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FIGURE 4. Breakdown of clinical outcomes and PET findings for patients who received adjuvant treatment after PET. Among patients who received adjuvant treatment, 20.6% (14/68) had IQ tumors and 79.4% (54/68) had OQ tumors.

 





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