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188Re-HDD/Lipiodol for Treatment of Hepatocellular Carcinoma: A Feasibility Study in Patients with Advanced Cirrhosis

Bieke Lambert, MD1, Klaus Bacher, MSc2, Katrien De Keukeleire, MD3, Peter Smeets, MD4, Isabelle Colle, MD, PhD5, Jae Min Jeong, PhD6, Hubert Thierens, PhD2, Roberto Troisi, MD, PhD7, Filip De Vos, PhD1 and Christophe Van de Wiele, MD, PhD1

1 Nuclear Medicine Division, Ghent University Hospital, Gent, Belgium
2 Department of Medical Physics, Ghent University, Gent, Belgium
3 Department of Vascular and Interventional Radiology, Ghent University Hospital, Gent, Belgium
4 Department of Radiology, Ghent University Hospital, Gent, Belgium
5 Division of Gastroenterology, Ghent University Hospital, Gent, Belgium
6 Department of Nuclear Medicine, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
7 Division of Abdominal Surgery, Ghent University Hospital, Gent, Belgium



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  		FIGURE 1. Anterior (A) and posterior (B) view of whole- body scintigraphy (patient 12) 28 h after administration of 3.7 GBq 188Re-HDD/lipiodol. (C) Illustration of ROI definitions on geometric mean combination of posterior and anterior view: liver (1), lungs (2), whole body (3), background to liver (4), background to lungs (5).

 


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  		FIGURE 2. Changes in white blood cells (A), platelets (B), bilirubin (C), AST (D), and ALT (E) over time.

 




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