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Sympathetic Denervation and Reinnervation After the Maze Procedure

¹ Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan
² Department of Cardiovascular Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan
³ Department of Health Sciences, Hokkaido University Graduate School of Medicine, Sapporo, Japan

View larger version (13K): [in a new window]   FIGURE 1. Serial changes of LVEFs in both groups: Maze+ (A) and Maze– (B). Pre = preoperative LVEF; 10 d = LVEF 10 d after surgery; 1 y = LVEF 1 y after surgery.

View larger version (12K): [in a new window]   FIGURE 2. Serial changes in H/Ms of both groups: Maze+ (A) and Maze– (B). Pre = preoperative H/M; 10 d = H/M 10 d after surgery; 1 y = H/M 1 y after surgery.

View larger version (12K): [in a new window]   FIGURE 3. Serial changes in WRs of both groups: Maze+ (A) and Maze– (B). Pre = preoperative WR; 10 d = WR 10 d after surgery; 1 y = WR 1 y after surgery.

View larger version (67K): [in a new window]   FIGURE 4. A 68-y-old man (patient 2) who had undergone MV replacement with Maze procedure. Reduction in uptake of 123I-MIBG and increase in WR were observed 10 d after surgery in lateral region (arrows). These changes resolved 1 y after surgery. Pre = preoperative images; 10 d = images 10 d after surgery; 1 y = images 1 y after surgery; SA = short-axis images; HLA = horizontal long-axis images.

View larger version (55K): [in a new window]   FIGURE 5. A 60-y-old woman (patient 12) who had undergone MV replacement without Maze procedure. Distribution of 123I-MIBG exhibited no regional change after surgery. Pre = preoperative images; 10 d = images 10 d after surgery; 1 y = images 1 y after surgery; SA = short-axis images; HLA = horizontal long-axis images.

View larger version (12K): [in a new window]   FIGURE 6. Correlation between changes in H/M, WR, and LVEF: correlation between changes in H/M and LVEF (A) and that between changes in WR and LVEF (B). •, Changes between before surgery and 10 d after surgery in Maze+ group; , those of Maze– group; , changes between 10 d and 1 y after surgery in Maze+ group; , those of Maze– group.