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18F-FDG PET for Evaluation of Bone Marrow Infiltration in Staging of Lymphoma: A Meta-Analysis

Emilios E. Pakos, MD1, Andreas D. Fotopoulos, MD2 and John P.A. Ioannidis, MD1,3,4

1 Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
2 Department of Nuclear Medicine, University Hospital of Ioannina, School of Medicine, Ioannina, Greece
3 Biomedical Research Institute, Foundation for Research and Technology–Hellas, Ioannina, Greece
4 Department of Medicine, Institute for Clinical Research and Health Policy Studies, Tufts–New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts



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FIGURE 1. Summary SROC curve analysis shows ability of 18F-FDG PET to evaluate bone marrow infiltration in patients with lymphoma. Each study is shown by an ellipse demonstrating sensitivity and specificity of 18F-FDG PET along with lines extending to respective 95% CIs. BMB is reference standard. Ellipse axes are proportional to weight of study in specificity and sensitivity dimensions. Data are summarized with weighted (thick line) and unweighted (thin line) SROC curves.

 





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