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Optimizing Imaging Protocols for Overweight and Obese Patients: A Lutetium Orthosilicate PET/CT Study

Benjamin S. Halpern, MD1, Magnus Dahlbom, PhD1, Martin A. Auerbach, MD1, Christiaan Schiepers, MD, PhD1, Barbara J. Fueger, MD1, Wolfgang A. Weber, MD1, Daniel H.S. Silverman, MD, PhD1, Osman Ratib, MD, PhD2 and Johannes Czernin, MD1

1 Department of Molecular and Medical Pharmacology, Ahmanson Biological Imaging Center, UCLA David Geffen School of Medicine, Los Angeles, California
2 Department of Radiological Sciences, UCLA David Geffen School of Medicine, Los Angeles, California



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FIGURE 1. Images of 38-y-old, 114-kg (250 lb) patient with breast cancer. Small focus of increased glycolytic activity (arrows) seen on 1, 3, 5, and 7 min/bed position scans corresponded to enlarged lymph nodes on CT. Despite considerable noise on 1 and 3 min/bed position scans, lesion was identified even on these short scans.

 


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FIGURE 2. Images of 54-y-old, 93-kg (205 lb) patient with lymphoma. Small focus of increased 18F-FDG uptake (arrows) seen in right upper abdomen corresponded to 1.1-cm perihepatic lymph node. Because of substantial image noise, this lesion was missed on 1 and 2 min/bed position scans.

 





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