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Bone-Seeking Radionuclides For Therapy

Royal Marsden Hospital, Sutton, England, United Kingdom

View larger version (62K): [in a new window]   FIGURE 1. (A) Posterior whole-body 99mTc-MDP bone image of patient with hormone-refractory prostate cancer. (B) Pain sites (cross-hatched) correlate exactly with foci of increased osteoblastic activity.

View larger version (36K): [in a new window]   FIGURE 2. Unsuspected bilateral vesicoureteric junction obstruction in advanced prostate cancer. Lumbar discomfort was relieved by ureteric stenting. Targeted radionuclide therapy would not have controlled dominant symptom, and poor excretion might have increased renal and whole-body doses.

View larger version (31K): [in a new window]   FIGURE 3. 99mTc-MDP bone image of patient with early metastases.

View larger version (33K): [in a new window]   FIGURE 4. 99mTc-MDP bone image of patient with diffuse metastases.