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Detection and Localization of Prostate Cancer: Correlation of 11C-Choline PET/CT with Histopathologic Step-Section Analysis

Mohsen Farsad, MD1, Riccardo Schiavina, MD2, Paolo Castellucci, MD1, Cristina Nanni, MD1, Barbara Corti, MD3, Giuseppe Martorana, MD2, Romeo Canini, MD4, Walter Grigioni, MD3, Stefano Boschi, ScD1, Mario Marengo, ScD1, Cinzia Pettinato, ScD1, Eugenio Salizzoni, MD4, Nino Monetti, MD1, Roberto Franchi, MD1 and Stefano Fanti, MD1

1 Nuclear Medicine Department, PET Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy
2 Urology Department, Università di Bologna, Bologna, Italy
3 Pathology Department, Università di Bologna, Bologna, Italy
4 Radiology Department, Università di Bologna, Bologna, Italy



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  		FIGURE 1. PET/CT results and histologic matching.

 


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  		FIGURE 2. Patient 6: Coronal PET images show 2 foci of pathologic uptake in left and right mid regions (arrows), confirmed to be the only foci of cancer on histologic examination.

 


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  		FIGURE 3. Correlation between SUVmax and lesion type.

 


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  		FIGURE 4. Patient 36: Transaxial PET/CT images show 1 focus of pathologic uptake in anterior transitional zone (arrow). First biopsy failed to detect cancer foci, whereas repeated biopsy using PET/CT images detected sites of cancer.

 




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