Comparison of Different Quantitative Approaches to 18F-Fluoride PET Scans
Winfried Brenner, MD, PhD1,
Cheryl Vernon, BS1,
Mark Muzi, MS2,
David A. Mankoff, MD, PhD1,
Jeanne M. Link, PhD1,
Ernest U. Conrad, MD3 and
Janet F. Eary, MD1
1 Division of Nuclear Medicine, University of Washington Medical Center, Seattle, Washington
2 Department of Radiology, University of Washington Medical Center, Seattle, Washington
3 Department of Orthopedics, University of Washington Medical Center, Seattle, Washington
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FIGURE 1. Three-compartment, 4-parameter model for fluoride bone metabolism.
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FIGURE 2. Diagram of ROI placement over femoral graft and contralateral normal femur.
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FIGURE 3. Positive linear correlation of KPat (mL/min/mL) and KNLR (mL/min/mL) for 18F-fluoride (KNLR = 1.0731 KPat; r = 0.99; P < 0.01).
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FIGURE 4. Positive linear correlation of SUV and KPat (mL/min/mL) for 18F-fluoride (KPat = 0.0065 SUV; r = 0.95; P < 0.01).
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FIGURE 5. Positive linear correlation of SUV and KNLR (mL/min/mL) for 18F-fluoride (KNLR = 0.0070 SUV; r = 0.93; P < 0.01).
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Copyright © 2004 by the Society of Nuclear Medicine.
