JNM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in JNM
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Koort, J. K.
Right arrow Articles by Aro, H. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Koort, J. K.
Right arrow Articles by Aro, H. T.

Comparative 18F-FDG PET of Experimental Staphylococcus aureus Osteomyelitis and Normal Bone Healing

Jyri K. Koort, MD1, Tatu J. Mäkinen, MD1, Juhani Knuuti, MD, PhD2, Jari Jalava, PhD3 and Hannu T. Aro, MD, PhD1

1 Orthopaedic Research Unit, Department of Surgery, University of Turku, Turku, Finland
2 Turku PET Centre, University of Turku, Turku, Finland
3 Department of Human Microbial Ecology and Inflammation, National Public Health Institute, Turku, Finland



View larger version (55K):

[in a new window]
  		FIGURE 1. Sequential 18F-FDG PET images of rabbit tibias at 3 and 6 wk (top and bottom, respectively). In the control animal (left), the healing-bone region shows a marked decrease in 18F-FDG activity by 6 wk (SUV ratios, 1.9 and 1.2 at 3 and 6 wk, respectively). In the experimental animal (right), the corresponding bone region with osteomyelitis shows continuous 18F-FDG uptake (SUV ratios, 3.1 and 5.5 at 3 and 6 wk, respectively).

 


View larger version (117K):

[in a new window]
  		FIGURE 2. Sequential pQCT images of rabbit tibias at 3 and 6 wk (top and bottom, respectively). In the control animal (left), closure of the cortical window is already seen at 3 wk. In the experimental animal, with an osteomyelitic bone (right), no apparent closure of the cortical window is seen at 3 wk and the cortical window is still open at 6 wk.

 


View larger version (107K):

[in a new window]
  		FIGURE 3. Plain radiographs demonstrating a healing defect (arrow) of the proximal tibia in a control animal (left) and a localized osteomyelitic defect (arrows) in an experimental animal (right).

 


View larger version (22K):

[in a new window]
  		FIGURE 4. 18F-FDG activity in intact bones, healing bone defects, and osteomyelitic regions. SUV ratios were calculated between operated and nonoperated sides.

 




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY THE JOURNAL OF NUCLEAR MEDICINE
Copyright © 2004 by the Society of Nuclear Medicine.