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Effects of Intravenous Atrial Natriuretic Peptide on Cardiac Sympathetic Nerve Activity in Patients with Decompensated Congestive Heart Failure

¹ Department of Cardiovascular Medicine, Gunma University School of Medicine, Maebashi, Japan
² Cardiovascular Hospital of Central Japan, Gunma, Japan

View larger version (9K): [in a new window]   FIGURE 1. Comparison of cardiac 123I-MIBG scintigraphic findings for total defect score (A), H/M count ratio (B), and washout rate (C) 3 wk after treatment. *P < 0.01 compared with group A; P = 0.0001 compared with group A; P < 0.05 compared with group A.

View larger version (47K): [in a new window]   FIGURE 2. Representative SPECT 123I-MIBG images 3 wk after treatment for both groups.

View larger version (89K): [in a new window]   FIGURE 3. Representative anterior planar delayed 1123I-MIBG images 3 wk after treatment for both groups. In these 2 examples, delayed H/M count ratio and washout rate were 1.94 and 40%, respectively, for a patient from group A and 1.48 and 53%, respectively, for a patient from group B.