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Predictive Value for Disease Progression of Serum Thyroglobulin Levels Measured in the Postoperative Period and After 131I Ablation Therapy in Patients with Differentiated Thyroid Cancer

Michel Toubeau, MD1, Claude Touzery, PhD1, Patrick Arveux, MD2, Gilles Chaplain, MD3, Geneviève Vaillant, MD4, Alina Berriolo, MD1, Jean-Marc Riedinger, PhD1, Christophe Boichot, MD1, Alexandre Cochet, MD1 and François Brunotte, MD1

1 Department of Nuclear Medicine, Centre Georges François Leclerc, Dijon, France
2 Department of Medical Statistics, Centre Georges François Leclerc, Dijon, France
3 Department of Radiotherapy, Centre Georges François Leclerc, Dijon, France
4 Department of Endocrinology, University Hospital, Dijon, France



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FIGURE 1. Progression-free survival curves according to initial lymph node status. There was no significant difference (P = 0.18) between pN0 and pNx patients. A significant difference was found between pN0 and pN1 (P = 0.0001) and between pNx and pN1 (P < 0.0001).

 


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FIGURE 2. Progression-free survival curves according to Tg1 level measured in postoperative period just before IAT.

 


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FIGURE 3. Progression-free survival curves according to Tg2 level measured 6–12 mo after IAT.

 





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