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Preparation of Patients with Thyroid Cancer for 131I Scintigraphy or Therapy by 1–3 Weeks of Thyroxine Discontinuation

Perry W. Grigsby, MD1,2, Barry A. Siegel, MD2,3, Simon Bekker, BA1, William E. Clutter, MD4 and Jeffrey F. Moley, MD2,5

1 Department of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri
2 Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri
3 Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri
4 Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri
5 Department of Surgery, Washington University School of Medicine, St. Louis, Missouri



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FIGURE 1. (A) Scatter plot of first TSH measurements as a function of time after total thyroidectomy (n = 176). (B) Cumulative frequency of TSH concentrations > 30 µIU/mL as a function of time after total thyroidectomy (n = 176).

 


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FIGURE 2. (A) Scatter plot of first TSH measurements as a function of time after abrupt T4 withdrawal (n = 108). (B) Cumulative frequency of TSH concentrations > 30 µIU/mL as a function of time after abrupt T4 withdrawal (n = 108).

 





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