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Normal and Abnormal 18F-FDG Endometrial and Ovarian Uptake in Pre- and Postmenopausal Patients: Assessment by PET/CT

Hedva Lerman, MD1, Ur Metser, MD1, Dan Grisaru, MD, PhD2,3, Ami Fishman, MD3,4, Gennady Lievshitz, MD1 and Einat Even-Sapir, MD, PhD1,3

1 Department of Nuclear Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel
2 Department of Gynecology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel
3 Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
4 Departmentof Obstetrics and Gynecology, Sapir Medical Center, Kfar Sava, Israel



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  		FIGURE 1. Summary of patient population data.

 


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  		FIGURE 2. Endometrial 18F-FDG uptake (SUV ± SD) during normal menstruation cycle.

 


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  		FIGURE 3. Menstruation. (A) Axial PET/CT image shows increased endometrial 18F-FDG (arrows point to endometrial cavity on, from left to right, CT, PET, and fusion images). (B) Sagittal PET/CT image shows a linear increased 18F-FDG uptake in the endometrium (arrows point to endometrial cavity on, from left to right, CT, PET, and fusion images).

 


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  		FIGURE 4. Cervical carcinoma. (A) Axial PET/CT image shows intense abnormal 18F-FDG uptake in the cervical tumor (arrows point to tumor on, from left to right, CT, PET, and fusion images). (B) Sagittal PET/CT image shows the primary cervical tumor (arrowheads on, from left to right, CT, PET, and fusion images) and a distended endometrial cavity surrounded by increased 18F-FDG uptake and uterine fluid collection. The surgical pathology report showed no evidence of endometrial involvement.

 


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  		FIGURE 5. From left to right, CT, PET, and fusion images of increased ovarian uptake. (A) Ovulation in a 27-y-old patient. Axial PET/CT image shows increased 18F-FDG uptake in the margin of a left ovarian functional cyst (arrows). (B) Ovarian cancer in a 56-y-old patient. Axial PET/CT image shows increased 18F-FDG uptake in the right ovarian tumor (arrows).

 




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