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99mTc-Stannous Colloid White Cell Scintigraphy in Childhood Inflammatory Bowel Disease

Kenneth Peacock, MB BS1, Ute Porn, MD2, Robert Howman-Giles2, Edward O’Loughlin1, Roger Uren2, Kevin Gaskin1, Stuart Dorney1 and Ramanand Kamath1

1 Department of Gastroenterology, The Children’s Hospital at Westmead, Sydney, New South Wales, Australia
2 Department of Nuclear Medicine, The Children’s Hospital at Westmead, Sydney, New South Wales, Australia



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FIGURE 1. Flow diagram of study population.

 


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FIGURE 2. An 8-y-old girl with Crohn’s disease. (A) Anterior (left) and posterior (right) 3-h planar images. Marked uptake of tracer is present in the distal ileum and in the ascending, transverse, and descending colon. Note the high degree of hepatic uptake, which impairs detection of upper gastrointestinal disease. There is no bladder activity. (B) Coronal 3-h SPECT images. Coronal SPECT more clearly delineates the distal ileal disease.

 


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FIGURE 3. A 13-y-old boy with Crohn’s disease. (A) Anterior (left) and posterior (right) 3-h planar images. Marked uptake of tracer is present throughout the colon, particularly in the distal ileum. (B) Small-bowel series of the terminal ileum. Abnormal separation of bowel loops is seen in the right iliac fossa, with bowel wall thickening. Normal mucosal pattern and terminal ileum peristalsis are present.

 





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