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18F-FLT PET for Visualization of Laryngeal Cancer: Comparison with 18F-FDG PET

David C.P. Cobben, MD1,2, Bernard F.A.M. van der Laan, MD, PhD3, Bram Maas, BSc1, Willem Vaalburg, MSc, PhD1, Albert J.H. Suurmeijer, MD, PhD4, Harald J. Hoekstra, MD, PhD2, Pieter L. Jager, MD, PhD1 and Philip H. Elsinga, MsC, PhD1

1 PET Center, Groningen University Hospital, Groningen, The Netherlands
2 Department of Surgical Oncology, Groningen University Hospital, Groningen, The Netherlands
3 Department of Otorhinolaryngology–Head and Neck Surgery, Groningen University Hospital, Groningen, The Netherlands
4 Department of Pathology and Laboratory Medicine, Groningen University Hospital, Groningen, The Netherlands



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FIGURE 1. Coronal 18F-FDG PET (A) and 18F-FLT PET (B) images of patient 3, diagnosed with primary laryngeal cancer. With both imaging modalities, uptake of the tracer in the laryngeal region can be observed. Maximum 18F-FDG SUV was 3.2, and maximum 18F-FLT SUV was 1.2. Physiologic 18F-FDG uptake can be seen in the muscles of the neck, and physiologic 18F-FLT uptake can be seen in the bone marrow of the ribs and sternum.

 





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