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Efficacy Assessment of Cerebral Arterial Bypass Surgery Using Statistical Parametric Mapping and Probabilistic Brain Atlas on Basal/Acetazolamide Brain Perfusion SPECT

Ho-Young Lee, MD1, Jin Chul Paeng, MD1, Dong Soo Lee, MD1, Jae Sung Lee, PhD1, Chang Wan Oh, MD2, Maeng Jae Cho, MD3, June-Key Chung, MD1 and Myung Chul Lee, MD1

1 Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea
2 Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea
3 Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea



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  		FIGURE 1. Comparison of pre- and postoperative images using SPM. Basal images show scattered areas of improvement, whereas acetazolamide images show more extensive areas of improvement. CVRI images show more confined areas of improvement around the proximal MCA territory.

 


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  		FIGURE 2. Changes in the numbers of significant voxels on SPM. The numbers of significant voxels in comparison with the control group represent the extent of the abnormality. The postoperative numbers of voxels were significantly lower than the preoperative numbers.

 


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  		FIGURE 3. Changes in the ICA territory counts using the probabilistic brain atlas. The basal and acetazolamide counts of all but 2 patients improved after surgery. One patient, showing a significant decrease in counts, was proven to have a perioperative cerebral infarct.

 




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