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Comparison of Gated PET with MRI for Evaluation of Left Ventricular Function in Patients with Coronary Artery Disease

Riemer H.J.A. Slart, MD1,2, Jeroen J. Bax, MD, PhD3, Richard M. de Jong, MD, PhD4, Jaep de Boer, MD, PhD1, Hildo J. Lamb, PhD5, Piet H. Mook, PhD6, Antoon T.M. Willemsen, PhD2, Willem Vaalburg, PhD2, Dirk J. van Veldhuisen, MD, PhD4 and Pieter L. Jager, MD, PhD1,2

1 Department of Nuclear Medicine, Groningen University Medical Center, Groningen, The Netherlands
2 PET-Center, Groningen University Medical Center, Groningen, The Netherlands
3 Department of Cardiology, University Medical Center, Leiden, The Netherlands
4 Department of Cardiology, Groningen University Medical Center, Groningen, The Netherlands
5 Department of Radiology, University Medical Center, Leiden, The Netherlands
6 Department of Radiology, Groningen University Medical Center, Groningen, The Netherlands



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  		FIGURE 1. Images from QGS of end-diastolic (A) and end-systolic (B) phases showing epicardial and endocardial borders of the left ventricle. SEPT = septal; LAT = lateral.

 


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  		FIGURE 2. Transverse 2-chamber view of end-diastolic (A) and end-systolic (B) phases of the left ventricle. Epicardial and endocardial contours are automatically drawn, but incorrect contours can be corrected manually.

 


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  		FIGURE 3. Relationship between summed wall motion scores (WMS) per patient on MRI and on gated 18F-FDG PET.

 


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  		FIGURE 4. Agreement between regional wall motion scores per segment on MRI and on gated 18F-FDG PET. Basal segments: 1 = anterior; 2 = lateral; 3 = inferior; 4 = septal. Distal segments: 5 = anterior; 6 = lateral; 7 = inferior; 8 = septal. 9 = apical segment. Mean = mean agreement for all 9 segments ± SEE.

 


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  		FIGURE 5. (A) Relationship between LVESV assessed by MRI and gated 18F-FDG PET. (B) Bland–Altman plot for LVESV without a systematic trend.

 


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  		FIGURE 6. (A) Relationship between LVEDV assessed by MRI and gated 18F-FDG PET. (B) Bland–Altman plot for LVEDV without a systematic trend.

 


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  		FIGURE 7. (A) Relationship between LVEF assessed by MRI and gated 18F-FDG PET. (B) Bland–Altman plot for LVEF without a systematic trend.

 




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