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Reduced Oxidative Metabolic Response in Dysfunctional Myocardium with Preserved Glucose Metabolism but with Impaired Contractile Reserve

¹ Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan
² Department of Tracer Kinetics, Hokkaido University Graduate School of Medicine, Sapporo, Japan
³ Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
⁴ Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan

View larger version (10K): [in a new window]   FIGURE 1. Comparison of myocardial oxidative metabolism at rest and during dobutamine (7.5 µg/kg/min) infusion. *P < 0.03; **P < 0.005; ***P < 0.001.

View larger version (16K): [in a new window]   FIGURE 2. Oxidative metabolic response to dobutamine (change in k mono). *P < 0.03; **P < 0.005.