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18F-FDG PET for Evaluation of the Treatment Response in Patients with Gastrointestinal Tract Lymphomas

Rakesh Kumar, MD, Yan Xiu, MD, Scott Potenta, BA, Ayse Mavi, MD, Hongming Zhuang, MD, PhD, Jian Q. Yu, MD, Thiruvekatasamy Dhurairaj, MD, Simin Dadparvar, MD and Abass Alavi, MD

Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania



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  		FIGURE 1. (A) Pretreatment 18F-FDG PET scans showing intense 18F-FDG uptake in the region of the cecum and ascending colon. (B) Posttreatment 18F-FDG PET scans showing no abnormal 18F-FDG uptake in the abdomen.

 


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  		FIGURE 2. Kaplan-Meier estimate of disease-free interval in 13 patients with negative 18F-FDG PET results and 6 patients with positive 18F-FDG PET results. Time intervals are in months.

 


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  		FIGURE 3. (A) Pretreatment 18F-FDG PET scans showing intense irregular 18F-FDG uptake in bowel loops. (B) Posttreatment 18F-FDG PET scans showing no abnormal 18F-FDG uptake in the abdomen. (C) Pretreatment pelvic CT scan of same patient showing irregular wall thickening of small bowel loops (arrow). (C) Posttreatment pelvic CT scan still showing irregular wall thickening of small bowel loops (arrow) suggestive of residual disease, even though 18F-FDG PET scans appeared normal.

 


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  		FIGURE 4. Kaplan-Meier estimate of disease-free interval in 10 patients with negative CT results and 9 patients with positive CT results. Time intervals are in months.

 


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  		FIGURE 5. Kaplan-Meier estimate of disease-free interval in 6 patients with positive PET results and 9 patients with positive CT results. Time intervals are in months.

 




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