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¹²³I-FP-CIT SPECT Imaging of Dopamine Transporters in Patients with Cerebrovascular Disease and Clinical Diagnosis of Vascular Parkinsonism

¹ Department of Nuclear Medicine, Edith Wolfson Medical Center, Holon, Israel
² Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel
³ Department of Neurology, Rabin Medical Center, Petah Tiqva, Israel
⁴ Department of Neurology, Edith Wolfson Medical Center, Holon, Israel

View larger version (54K): [in a new window]   FIGURE 1. Illustration of region-of-interest placement on caudate and putamen.

View larger version (14K): [in a new window]   FIGURE 2. 123I-FP-CIT binding in different striatal regions in patients with good response and in patients with poor response to L-dopa therapy. ASGR = abnormal study with good response; ASPR = abnormal study with poor response; NSPR = normal study with poor response; SR = right striatum; SL = left striatum; CR = right caudate; CL = left caudate; PR = right putamen; PL = left putamen; P/C R = putamen-to-caudate ratio on right; P/C L = putamen-to-caudate ratio on left.

View larger version (56K): [in a new window]   FIGURE 3. 123I-FP-CIT SPECT of 5 patients with good response to therapy (upper row: left, middle, and right; and lower row: left and middle) and patient with poor response to therapy (lower row: right; patient 7).