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Functional Changes After Partial Left Ventriculectomy and Mitral Valve Repair Assessed by Gated Perfusion SPECT

¹ Department of Nuclear Medicine, University Hospital, Münster, Germany
² Institute of Arteriosclerosis Research, Westfälische Wilhelms-University, Münster, Germany
³ Department of Cardiology and Angiology, University Hospital, Münster, Germany
⁴ Department of Cardiothoracic Surgery, University Hospital, Münster, Germany
⁵ Department of Anesthesiology and Operative Intensive Care, University Hospital, Münster, Germany

View larger version (15K): [in a new window]   FIGURE 1. LVEDD (A) and LVESD (B) diameters before, early (3 mo), and late (12 mo) after PLV–MVR measured by echocardiography. Numbers in bars represent number of patients investigated for each time point (8 patients were measured serially). *P < 0.05; **P < 0.01; ***P < 0.001; ns equals P = not significant.

View larger version (47K): [in a new window]   FIGURE 2. Three-dimensional left ventricular reconstruction (lateral view, end-diastolic image) projecting regional myocardial perfusion measured by gated SPECT preoperatively (pre) as well as 1 mo (early) and 12 mo (late) after PLV–MVR. Note that posterolateral scar in area of surgical suture after surgery seems to shrink in time interval from 1 to 12 mo.

View larger version (12K): [in a new window]   FIGURE 3. Results of gated perfusion SPECT before (17 ± 23 d) as well as early (38 ± 28 d) and late (296 ± 130 d) after PLV–MVR. End-diastolic (EDV, A) and end-systolic (ESV, B) left ventricular volumes and EF (C) are displayed. Numbers in bars represent number of patients investigated for each time point (7 patients were measured serially). *P < 0.05; ***P < 0.001; ns equals P = not significant.

View larger version (13K): [in a new window]   FIGURE 4. Results of gated perfusion SPECT before (17 ± 23 d) as well as early (38 ± 28 d) and late (296 ± 130 d) after PLV–MVR. Myocardial volume (A) and scar volumes (B) are displayed. Numbers in bars represent number of patients investigated for each time point (7 patients were measured serially). ***P < 0.001; ns equals P = not significant.