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Validation of QGS and 4D-MSPECT for Quantification of Left Ventricular Volumes and Ejection Fraction from Gated 18F-FDG PET: Comparison with Cardiac MRI

Wolfgang M. Schaefer, MD, PhD1, Claudia S.A. Lipke, MD2, Bernd Nowak, MD1, Hans-Juergen Kaiser, PhD1, Patrick Reinartz, MD1, Arno Buecker, MD3, Gabriele A. Krombach, MD3, Udalrich Buell, MD1 and Harald P. Kühl, MD2

1 Department of Nuclear Medicine, University Hospital, University of Aachen, Aachen, Germany
2 Medical Clinic I, University Hospital, University of Aachen, Aachen, Germany
3 Department of Radiology, University Hospital, University of Aachen, Aachen, Germany



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  		FIGURE 1. Correlation analysis of EDV estimated with QGS (A) and 4D-MSPECT (C) from gated 18F-FDG PET and cMRI. Bland-Altman plots compare QGS versus cMRI (B) and 4D-MSPECT versus cMRI (D). 4DM = 4D-MSPECT; gFDG-PET and gPET = gated 18F-FDG PET.

 


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  		FIGURE 2. Correlation analysis of ESV estimated with QGS (A) and 4D-MSPECT (C) from gated 18F-FDG PET and cMRI. Bland-Altman plots compare QGS versus cMRI (B) and 4D-MSPECT versus cMRI (D). 4DM = 4D-MSPECT; gFDG-PET and gPET = gated 18F-FDG PET.

 


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  		FIGURE 3. Correlation analysis of LVEF estimated with QGS (A) and 4D-MSPECT (C) from gated 18F-FDG PET and cMRI. Bland-Altman plots compare QGS versus cMRI (B) and 4D-MSPECT versus cMRI (D). 4DM = 4D-MSPECT; gFDG-PET and gPET = gated 18F-FDG PET.

 


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  		FIGURE 4. Correlation analysis of EDV (A), ESV (C), and LVEF (E) estimated with QGS and 4D-MSPECT from gated 18F-FDG PET. Bland-Altman plots compare QGS versus 4D-MSPECT for EDV (B), ESV (D), and LVEF (F). 4DM = 4D-MSPECT; gFDG-PET = gated 18F-FDG PET.

 




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