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18F-Fluorothymidine Radiation Dosimetry in Human PET Imaging Studies

Hubert Vesselle, PhD, MD1, John Grierson, PhD1, Lanell M. Peterson, BA1, Mark Muzi, MS1, David A. Mankoff, MD, PhD1 and Kenneth A. Krohn, PhD1

1 Department of Radiology, Division of Nuclear Medicine, University of Washington Medical Center, Seattle, Washington



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FIGURE 1. Time-activity curves for 3 source organs (liver, marrow, kidney) in 1 patient normalized to 37-MBq injected dose of 18F-FLT and to 73.7-kg weight.

 


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FIGURE 2. Five fully sampled bladder time-activity curves and curve fit to data. Each patient is represented by a different symbol. Solid line represents data fit calculated according to Equation 2.

 





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