18F-FDG PET of Patients with Hürthle Cell Carcinoma
Val J. Lowe, MD1,
Brian P. Mullan, MD1,
Ian D. Hay, MD2,
Brian McIver, MD2 and
Jan L. Kasperbauer, MD3
1 Department of Radiology, Division of Nuclear Medicine, Mayo Clinic, Rochester, Minnesota
2 Department of Endocrinology, Mayo Clinic, Rochester, Minnesota
3 Department of Surgery, Division of Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota
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FIGURE 1. PET image of patient 2, who had history of Hürthle cell cancer and returned with complaint of diffuse aches. Single indeterminate lung nodule with some mediastinal adenopathy was seen on CT. Sonography and 131I scans had negative findings. PET image showed widespread bone and lung metastases, which were confirmed with right hilar biopsy.
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FIGURE 2. PET image of patient 8, who had Hürthle cell cancer previously treated and who returned with elevated thyroglobulin level (800 ng/mL) for evaluation. Neck sonography and 131I scan had negative findings. PET image showed lung, vertebral body, and pelvis/femur (arrow) metastases. Biopsy of pelvis confirmed metastatic disease.
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FIGURE 3. PET image of patient 9, who had Hürthle cell cancer previously treated and who returned for follow-up evaluation. Neck sonography showed 1-cm right-neck lymph node suggestive of Hürthle cell cancer. PET image showed variable nonspecific uptake in neck and chest, and no definite tumor was believed to be present. Biopsy 2 mo later of region seen on sonography confirmed disease (2/4 grade Hürthle cell cancer), which was also likely near right-lower-neck uptake seen on PET (arrow).
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Copyright © 2003 by the Society of Nuclear Medicine.
