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18F-FDG PET Versus CT for Evaluating the Spleen During Initial Staging of Lymphoma

Josephine N. Rini, MD1, John C. Leonidas, MD2, Maria B. Tomas, MD1 and Christopher J. Palestro, MD1

1 Division of Nuclear Medicine, Long Island Jewish Medical Center, New Hyde Park, New York
2 Pediatric Radiology, Long Island Jewish Medical Center, New Hyde Park, New York



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  		FIGURE 1. Stage IV non-Hodgkin’s lymphoma with splenic involvement in 77-y-old man (patient 4). (A) 18F-FDG PET image shows diffusely increased splenic uptake of 18F-FDG that is greater than hepatic uptake. S/L ratio was 1.9. (B) CT image shows multiple splenic hypodensities. Splenic index was 1,612 mL.

 


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  		FIGURE 2. Stage IVB nodular sclerosing Hodgkin’s disease and splenic involvement in 16-y-old female patient (patient 2). (A) 18F-FDG PET image shows diffusely increased splenic uptake of 18F-FDG that is more intense than hepatic uptake. S/L ratio was 2.2. (B) CT image shows homogeneous appearance of spleen. Splenic index of 780 mL was normal for age (normal = <=820 mL).

 


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  		FIGURE 3. Stage II nodular sclerosing Hodgkin’s disease in 20-y-old male patient (patient 1). (A) 18F-FDG PET image shows that intensity of 18F-FDG uptake in spleen was similar to that in liver. S/L ratio was 0.8. (B) CT image shows homogeneous appearance of spleen. However, splenic index of 1,458 mL (normal = <=480 mL) was elevated.

 




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