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rhTSH Stimulation Before Radioiodine Therapy in Thyroid Cancer Reduces the Effective Half-Life of 131I

Christian Menzel, MD, PhD, Wolfgang T. Kranert, ScD, Natascha Döbert, MD, Michaela Diehl, MD, Thomas Fietz, ScD, Nadja Hamscho, MD, Uwe Berner, MD and Frank Grünwald, MD, PhD

Department of Nuclear Medicine, Hospital of the Johann W. Goethe University, Frankfurt, Germany



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  		FIGURE 1. Age dependency of endogenous TSH incretion.

 


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  		FIGURE 2. Comparative evaluation of mean TSH values (plus 1 SD) for different groups with and without rhTSH stimulation and corresponding mean hTG levels. From left to right, bars represent groups A, B, C, D, and E.

 


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  		FIGURE 3. Effective half-life of therapeutic activities of radioiodine in patients after rhTSH stimulation (groups A and D) and after endogenous TSH stimulation (groups B, C, and E). From left to right, bars represent groups A, B, C, D, and E.

 




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