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SPECT Semiquantitative Analysis of Adrenocortical 131I-6ß-Iodomethyl-Norcholesterol Uptake to Discriminate Subclinical and Preclinical Functioning Adrenal Incidentaloma

Giuseppe La Cava, MD1, Alessio Imperiale, MD1, Catia Olianti, MD1, G. Riccardo Gheri, MD2, Cristina Ladu, MD2, Massimo Mannelli, MD2 and Alberto Pupi, MD1

1 Nuclear Medicine Unit, Department of Clinical Pathophysiology, University of Florence, Florence, Italy
2 Endocrinology Unit, Department of Clinical Pathophysiology, University of Florence, Florence, Italy



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FIGURE 1. Typical adrenal incidentaloma SPECT study at 72 h after 131I-NP-59 injection in patient classified, according to Reincke (8), as PC-CS. Scintigraphic study shows typical example of concordant pattern: increased radiotracer uptake on side of lesion demonstrated on CT scan (4 x 5 cm left corticoadrenal adenoma).

 


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FIGURE 2. Scatter plots show correlations between UPT% and some biochemical and radiologic parameters.

 





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